Genetic polymorphisms of the N-acetyltransferase genes and risk of Parkinson's disease

Academic Article


  • Recently, the authors demonstrated linkage in idiopathic PD to a region on chromosome 8p that contains the N-acetyltransferase genes, NAT1 and NAT2. The authors examined NAT1 and NAT2 for association with PD using family-based association methods and single nucleotide polymorphisms (SNPs). The authors did not find evidence for association with increased risk for PD between any individual NAT1 or NAT2 SNP or acetylation haplotype (N = 397 families, 1,580 individuals).
  • Authors

    Published In

  • Neurology  Journal
  • Digital Object Identifier (doi)

    Author List

  • Van der Walt JM; Martin ER; Scott WK; Zhang F; Nance MA; Watts RL; Hubble JP; Haines JL; Koller WC; Lyons K
  • Start Page

  • 1189
  • End Page

  • 1191
  • Volume

  • 60
  • Issue

  • 7