MiR-125a-5p regulates differential activation of macrophages and inflammation

Academic Article


  • Background: The role of miRNAs in macrophage polarization has not been well defined. Results: miR-125a-5p promotes M2, while it suppresses M1 macrophage polarization. Conclusion: miR-125a-5p is an important regulator of the differential activation of macrophages. Significance: Delineation of the role of miR-125a-5p in macrophage polarization provides insights into miRNA regulation of inflammation, tissue repair and tumor progression. © 2013 by The American Society for Biochemistry and Molecular Biology, Inc.
  • Published In

    Digital Object Identifier (doi)

    Author List

  • Banerjee S; Cui H; Xie N; Tan Z; Yang S; Icyuz M; Thannickal VJ; Abraham E; Liu G
  • Start Page

  • 35428
  • End Page

  • 35436
  • Volume

  • 288
  • Issue

  • 49