Comparison of the Suppression of Interferon Production and Inhibition of Its Action by Vitamin A and Related Compounds (39532)

Academic Article

Abstract

  • We have investigated the structural requirements for vitamin A suppression of interferon production and inhibition of interferon action. Inhibition of interferon action seems to be most dependent on the side chain of the vitamin A molecule. The side chain apparently requires a conjugated double bond system and a hy-drophilic terminal group to inhibit interferon action. In contrast, the ring portion of the vitamin A molecule seems to be most important for the suppression of interferon production. © 1976, SAGE Publications. All rights reserved.
  • Authors

    Digital Object Identifier (doi)

    Author List

  • Blalock JE; Gifford GE
  • Start Page

  • 298
  • End Page

  • 300
  • Volume

  • 153
  • Issue

  • 2