Effect of serum on the antiviral and anticellular activities of mouse interferon

Academic Article

Abstract

  • Fetal bovine serum markedly decreased the ability of mouse L-929 interferon preparations to inhibit the formation of L-929 clones, but did not affect their ability to inhibit vesicular stomatitis virus (VSV) plaque formation in these cells. This dissociation of effects by interferon preparations indicates that: 1. the mechanism of action of interferon for its anticlonal and antiviral activities is different; or 2. the molecule responsible for the anticlonal activity is a separate growth inhibitory factor. © 1978 Springer-Verlag.
  • Authors

    Published In

    Digital Object Identifier (doi)

    Author List

  • Kading VH; Blalock JE; Gifford GE
  • Start Page

  • 237
  • End Page

  • 242
  • Volume

  • 56
  • Issue

  • 3