Purified human immune interferon has more potent anticellular activity than fibroblast or leukocyte interferon

Academic Article


  • Human immune interferon preparations have anticellular activity on human cell lines (WISH and HEp-2). This anticellular activity copurified with the human immune interferon and appears to be a function of the immune interferon molecule. On the basis of a unit of antiviral activity, purified human immune interferon had about 20 and 100 times more anticellular activity than purified fibroblast or leukocyte interferon, respectively. The possible implications of this finding in the treatment of human neoplasia are discussed. © 1980.
  • Authors

    Published In

    Digital Object Identifier (doi)

    Author List

  • Blalock JE; Georgiades JA; Langford MP; Johnson HM
  • Start Page

  • 390
  • End Page

  • 394
  • Volume

  • 49
  • Issue

  • 2