Enhancement of the in vitro antibody response by thyrotropin

Academic Article


  • The pituitary hormone thyrotropin (TSH) has been shown to enhance in a dose dependent manner the in vitro antibody response. Highly purified preparations of bovine and human TSH enhanced up to 375% the number of cells producing antibody to sheep erythrocytes. TSH had to be present prior to 24-48h of the initiation of culture for enhancement of the antibody response. An analogy is discussed between TSH and B lymphocyte growth and differentiation factors. © 1984 Academic Press, Inc. All rights reserved.
  • Authors

    Digital Object Identifier (doi)

    Pubmed Id

  • 23473130
  • Author List

  • Blalock JE; Johnson HM; Smith EM; Torres BA
  • Start Page

  • 30
  • End Page

  • 34
  • Volume

  • 125
  • Issue

  • 1