An antibody to a peptide specified by an RNA that is complementary to γ-endorphin mRNA recognizes an opiate receptor

Academic Article

Abstract

  • The putative δ-opiate receptor complex has been identified by a new approach which employed an antibody that is directed against a peptide which binds γ-endorphin and is specified by RNA that is complementary to that of γ-endorphin mRNA. This antibody competes with β-endorphin and naloxone for binding sites on the surface of neuroblastoma × glioma NG108-15 hybrid cells. The opiate receptor complex has an apparent molecular weight of 210 000 and is composed of four noncovalently associated subunits with apparent molecular weights of 68 000, 58 000, 45 000 and 30 000. © 1986.
  • Authors

    Published In

    Digital Object Identifier (doi)

    Author List

  • Carr DJJ; Bost KL; Blalock JE
  • Start Page

  • 329
  • End Page

  • 337
  • Volume

  • 12
  • Issue

  • 4