Productions of neuroendocrine peptide hormones by the immune system

Academic Article


  • Similarities between the immune and neuroendocrine systems have been often noted. Among the newer of these is the observation in both systems of an increasing number of peptides and proteins that are used as intercellular messengers. Previous to the work which is herein reviewed, these molecules were largely deemed to be endogenous informational substances for the system from which they were originally isolated. Recent evidence, however, strongly supports the notion that neuroendocrine peptides are endogenous to the immune system and are used for both intraimmune system regulation, as well as for bidirectional communication between the immune and neuroendocrine systems.
  • Authors

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    Author List

  • Blalock JE
  • Start Page

  • 1
  • End Page

  • 13
  • Volume

  • 43