Pathophysiology of the pleura

Academic Article


  • The pleural mesothelial cell is an essential cell in maintaining the normal homeostasis of the pleural space and it is also a central component of the pathophysiologic processes affecting the pleural space. In this review, we will review the defense mechanisms of the pleural mesothelium and changes in pleural physiology as a result of inflammatory, infectious, and malignant conditions with a focus on cytokine and chemokine networks. We will also review the processes involved in the pathogenesis of pleural fibrosis. Copyright © 2008 S. Karger AG.
  • Digital Object Identifier (doi)

    Author List

  • Jantz MA; Antony VB
  • Start Page

  • 121
  • End Page

  • 133
  • Volume

  • 75
  • Issue

  • 2