An integrated genetic and physical map of the 650-kb region containing the congenital polycystic kidney (cpk) locus on mouse chromosome 12

Academic Article

Abstract

  • Mice homozygous for the congenital polycystic kidney (cpk) mutation develop a rapidly progressive form of polycystic kidney disease. We report an integrated genetic and physical map of the 650-kb region containing the cpk locus and the exclusion of Rrm2 and Idb2 as candidate cpk genes. Our study establishes the requisite foundation for positional cloning of the cpk gene. Copyright © 2001 S. Karger AG, Basel.
  • Authors

    Author List

  • Mrug M; Green WJ; Dasgupta S; Beier DR; Lu W; D'eustachio P; Guay-Woodford LM
  • Start Page

  • 55
  • End Page

  • 61
  • Volume

  • 94
  • Issue

  • 1-2