Delayed graft function after renal transplantation: Causes, implications, and clinical management

Academic Article

Abstract

  • Delayed allograft function complicates the course of cadaveric renal transplantation in 10-70% of cases. Its etiology is multifactorial, and its histology nondescript. Although advances in donor and recipient management, along with better organ preservation, may reduce the incidence of delayed function, expanding use of marginal donors is likely to sustain its frequency. In the recipient with delayed function, aggressive immunologic surveillance, prophylactic anti-lymphocyte therapy and use of calcium antagonists may shorten the duration of graft dysfunction, and attenuate its adverse impact on long-term outcome.
  • Authors

    Published In

    Author List

  • Gaston RS; Schlessinger SD
  • Start Page

  • 313
  • End Page

  • 321
  • Volume

  • 7
  • Issue

  • 6