Assessment of ventricular volumes using cine magnetic resonance in the intact dog: A comparison of measurement methods

Academic Article


  • Rationale, objective and methods. The authors recently combined magnetic resonance imaging with high-fidelity left ventricular (LV) pressure measurement in a closed-chested, intact animal model. However, LV volumes derived from sum-mated serial short axis slices require long imaging times and make it difficult to record LV volumes in response to acute alterations in load. In this study, geometry-based LV end-systolic volume estimates calculated from a single long-axis image (Area-Length formula) and from a long-axis and short-axis image (Bullet formula) were compared to those derived from summated short-axis images of the left ventricle (Simpson’s rule) during altered loading conditions in six anesthetized, intact dogs. results. Angiotensin infusion produced three different LV systolic pressures(89 ± 8 vs. 123 ± 12 vs. 151 ± 10 mmHg, P < .001). Area-Length and Bullet formula end-systolic volumes correlated with Simpson'srule volumes (r = .95 and .97; respectively). However, Bullet formula end-systolic volumes provided a significantly better agreement with Simpson's rule end-systolic volumes. conclusions. The Bullet formula can be substituted for Simpson's rule to record magnetic resonance LV volumes during steady-state alterations in load in our intact animal model. © 1994, J.B. Lippincott Company.
  • Pubmed Id

  • 26173858
  • Author List

  • Dell'italia LJ; Blackwell GG; Pearce DJ; Thorn B; Pohost GM
  • Start Page

  • 162
  • End Page

  • 167
  • Volume

  • 29