Bradycardia and syncope as a presentation of cardiac allograft rejection involving the conducting system

Academic Article


  • Post-heart transplantation bradycardic syncope and arrest could be due to preferential rejection of the conduction system. We present six heart transplant patients with this presentation, two of whom died. The autopsy of one of those patients demonstrated severe rejection of the conduction system, with only mild rejection throughout the rest of the myocardium. We postulate that aggressive therapy for rejection and pacemaker placement may result in improved survival in heart transplant recipients with this clinical presentation.
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    Digital Object Identifier (doi)

    Author List

  • Knight CS; Tallaj JA; Rayburn BK; Pamboukian SV; Bourge R; Kirklin JK; McGiffin D; Litovsky SH
  • Start Page

  • 117
  • End Page

  • 120
  • Volume

  • 19
  • Issue

  • 2