Tendon injuries in athletes' hands can be disabling and may lead to a chronic disability. These injuries may occur in the professional or recreational athlete and involve the flexor and extensor tendons of the hand and wrist. Overuse syndromes may be another cause of tendon injuries to the hand and wrist. Correct diagnosis of all these entities requires knowledge of anatomy, pathophysiology, and commonly occurring injuries to the athlete's hand and wrist. Treatment may be non-operative or surgical and tailored to the specific injury sustained and the athlete involved to yield the most reliable functional result.