Does midtrimester cervical length ≥25 mm predict preterm birth in high-risk women?

Academic Article


  • Objective: We sought to assess pregnancy outcome along a continuum of cervical lengths (CLs) ≥25 mm. Study Design: We conducted planned secondary analysis of a randomized cerclage trial of women with prior spontaneous preterm birth 170-346/7 weeks. Outcomes of women who maintained CLs ≥25 mm were analyzed. Women with CLs <25 mm randomized to no cerclage comprised an internal comparison group. Results: Of 1014 screened, 153 had CL <25 mm, and 672 had CL ≥25 mm. Birth <35 weeks occurred in 16% of the ≥25 mm cohort. The relationship between CLs ≥25 mm and birth gestational age was null (P = .15). In the <25 mm group, progressively shorter CLs predicted birth <35 weeks (P < .001); this relationship was null in the ≥25 mm group (P = .17). Conclusion: The continuum of CLs ≥25 mm measured between 160/7-226/7 weeks does not predict gestational length in women with prior spontaneous preterm birth. © 2010 Mosby, Inc. All rights reserved.
  • Digital Object Identifier (doi)

    Author List

  • Owen J; Szychowski JM; Hankins G; Iams JD; Sheffield JS; Perez-Delboy A; Berghella V; Wing DA; Guzman ER
  • Start Page

  • 393.e1
  • End Page

  • 393.e5
  • Volume

  • 203
  • Issue

  • 4