As Pakistan becomes industrialized, the development of human resources is essential to addressing emerging health problems. The Fogarty International Center (FIC)-funded University of Alabama at Birmingham (UAB)-Aga Khan University (AKU) ITREOH initiative has been instrumental in filling the gaps in environmental and occupational health (EOH) training and research. Because of travel impediments to Pakistan, a regional short-term training program was implemented in Nepal and Sri Lanka. Workshop participants were from Pakistan, Nepal, Sri Lanka, India, and Bangladesh. The training programs enhanced north-to-south and south-to-south collaboration in research and training in South Asia. A major impact is the development of a certificate program in EOH at AKU. Research initiatives of regional and/or global concern are also under way in the other participating countries. The combination of face-to-face training with Web-based interaction for follow-up was optimal for short-term training.