© The Author(s) 2015. Introduction: Occupational therapy practitioners who provide interventions for adults with low vision need to understand challenges with occupational performance from the individual's perspective in order to implement effective treatment. The purpose of this study was to understand self-described occupational behaviors of persons with low vision. Method: This qualitative study included semi-structured interviews regarding the occupational experiences of 22 individuals with varying levels of vision impairment. Transcribed data were organized according to the areas of occupation reported in the American Occupational Therapy Association's Practice Framework. Results: Participants described occupational performance of activities of daily living, instrumental activities of daily living, and leisure. Within each area of occupation, participants reported lighting, contrast, familiarity, and organization within the environment as facilitators or barriers to participation. Participants with increased vision loss relied heavily on assistive devices, task simplification, and others to perform desired occupations. Conclusion: The information obtained in this study can assist practitioners in selecting more effective interventions to increase the independence and safety of individuals with low vision.