Dentin and Bone: Similar Collagenous Mineralized Tissues



  • Teeth are individual organs consisting of an exposed crown structure and internally embedded root structure. Each tooth is an individual organ that is coordinated through location and function to form a highly ordered and symmetrical patterned unit known as the dentition. Humans have two successive sets of teeth, the primary dentition or baby teeth which are ultimately replaced by the permanent dentition. The tooth is unique in that it forms three distinct mineralized extracellular matrices, enamel, dentin and cementum, which are temporally and spatially integrated to form the hardest structure of the human body. The tooth crown is covered by an outer layer of enamel with an inner more resilient mineralized dentin layer in juxtaposition and then an unmineralized predentin matrix adjacent to the dental pulp chamber. In contrast, the root is covered by a thin outer layer of cementum over the inner layers of dentin and predentin. Therefore, the most abundant matrix of the tooth is that of dentin covering both the crown and root structures. In this chapter, we will explore dentin, the mineralized connective tissue of teeth, and compare and contrast its formation and structure with that of bone.
  • Edition

  • Sixth
  • Keywords

  • Medical
  • International Standard Book Number (isbn) 10

  • 1848828225
  • International Standard Book Number (isbn) 13

  • 9781848828223
  • Pubmed Id

  • 16195342
  • Start Page

  • 183
  • End Page

  • 200