Dual Primary IGH Translocations in Multiple Myeloma: A Novel Finding

Academic Article


  • • Cytogenetics in multiple myeloma is utilized to risk stratify patients into standard and high-risk groups. • Immunoglobulin heavy chain (IGH) gene translocations such as t(4;14) and t(14;16) are high-risk cytogenetic abnormalities that confer poor outcomes to therapy in multiple myeloma. • Primary IGH translocations are typically considered mutually exclusive events. • Here, we describe a case of multiple myeloma with dual primary IGH translocations involving both t(4;14) and t(14;16).
  • Digital Object Identifier (doi)

    Author List

  • Ravindran A; Greipp PT; Wongchaowart N; Smadbeck JB; Peterson JF; Ketterling RP; Kumar SK; Baughn LB
  • Start Page

  • e710
  • End Page

  • e713
  • Volume

  • 21
  • Issue

  • 9