Oral azole drugs as systemic antifungal therapy

Academic Article


  • To the Editor: The review of oral azole drugs for systemic antifungal therapy, by Como and Dismukes (Jan. 27 issue),1 was informative but lacked a discussion of the use of these agents in children. Clinicians who treat children have long been seeking an alternative to amphotericin B and have started using azole agents despite the lack of data on the pharmacokinetics, safety, and efficacy of these drugs in children. Ketoconazole is the azole most familiar to clinicians caring for children and is currently the only oral agent for which there is an established dose for children (5 to 10 mg. © 1994, Massachusetts Medical Society. All rights reserved.
  • Published In

    Digital Object Identifier (doi)

    Author List

  • Schutze GE; Etzel JV; Como JA; Dismukes WE
  • Start Page

  • 1759
  • End Page

  • 1760
  • Volume

  • 330
  • Issue

  • 24