Esthetics is one of the most important considerations in developing an orthodontic-orthognathic treatment plan. For patients with a Class III skeletal pattern, this multidisciplinary treatment option is designed to achieve adequate skeletal and functional enhancements and a harmonious esthetic outcome. This case report describes the orthodontic-orthognathic treatment of a 25-year-old female with skeletal Class III malocclusion, maxillary retrognathism, and anterior crossbite. The surgical plan included a maxillary LeFort I osteotomy and a mandibular bilateral sagittal split osteotomy. The double-jaw surgery combined with the orthodontic treatment improved her skeletal jaw relationship and occlusal function and resulted in excellent proportional facial esthetics.