Overweight and cystic fibrosis: An unexpected challenge

Academic Article


  • Achieving a healthy weight balance has been a central focus of care for people who have cystic fibrosis (CF). Over the years, the emphasis has primarily been on promoting weight gain to optimize pulmonary outcomes. With continued improvements in CF care, including highly effective CF modulators available for many people, the CF community is now experiencing a new challenge: addressing the concern that some people are gaining weight excessively. While at this time, we do not know to what extent overweight and obesity will affect health outcomes for people with CF, it is likely that excessive weight gain may have negative health impacts similar to those seen in the general population. In this paper, we review the history of nutritional guidelines for people with CF, as well as more recent trends toward overweight and obesity for some. A multidisciplinary approach is needed to collaboratively start the oftentimes difficult conversation regarding excessive weight gain, and to identify resources to help people achieve and maintain a healthy weight through diet, exercise, and behavioral modification.
  • Authors

    Published In

    Digital Object Identifier (doi)

    Author List

  • Gabel ME; Fox CK; Grimes RA; Lowman JD; McDonald CM; Stallings VA; Michel SH
  • Start Page

  • S40
  • End Page

  • S49
  • Volume

  • 57
  • Issue

  • S1