Bypass of A- and B-signaling requirements for Myxococcus xanthus development by mutations in spdR

Academic Article


  • Mutations in spdR, previously reported to bypass the developmental requirement for B-signaling in Myxococcus xanthus, also bypass the requirement for A-signaling but not C-, D-, or E-signaling. Mutations in spdR restored nearly wild-type levels of sporulation to representative A-signal-deficient mutants carrying asgA476, asgB480, and asgC767 and improved the quality of fruiting body formation in the asgB480 mutant. The defect in A-factor production by the asgB480 mutant was not restored in the spdR2134 asgB480 double mutant.
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    Author List

  • Tse H; Gill RE
  • Start Page

  • 1455
  • End Page

  • 1457
  • Volume

  • 184
  • Issue

  • 5