Right place, right time, and only once: Replication initiation in metazoans

Academic Article


  • DNA replication is tightly regulated at the initiation step by both the cell cycle machinery and checkpoint pathways. Here, we discuss recent advances in understanding how replication is initiated in metazoans at the correct chromosome positions, at the appropriate time, and only once per cell cycle. Copyright © 2005 by Elsevier Inc.
  • Authors

    Published In

  • Cell  Journal
  • Digital Object Identifier (doi)

    Author List

  • Machida YJ; Hamlin JL; Dutta A
  • Start Page

  • 13
  • End Page

  • 24
  • Volume

  • 123
  • Issue

  • 1