Synthesis, conformation and vibrational dynamics of the peptide -Ser-Cys-Lys-Leu-Asp-Phe-, a fragment of apolipoprotein B

Academic Article


  • The collective normal modes of the hexapeptide -Ser-Cys-Lys-Leu-Asp-Phe-, a fragment of apolipoprotein B (apo B), have been obtained. They reflect the dynamic nature and are atleast partly responsible for energy input in autolytic activity. Further, on energetic considerations based on the measurements reported by Sim & Sim, it has been shown that of the two such fragments only one induces autolysis, while the other remains anchored to the coated pit.
  • Authors


  • Amides/chemistry Animals Apolipoproteins B/*chemistry Autolysis Disulfides/chemistry Humans Models, Chemical Molecular Conformation Peptide Fragments/*chemistry Peptides/*chemistry Protein Conformation Spectroscopy, Fourier Transform Infrared/methods
  • Pubmed Id

  • 19237294
  • Author List

  • Srivastava S; Srivastava S; Melkani GC; Singh S; Gupta VD; Vijai Prakash G
  • Start Page

  • 410
  • End Page

  • 418
  • Volume

  • 39
  • Issue

  • 6