Cooperativity between Flt3/Syk and Proteasome Inhibitors in Flt3mutant/Wildtype AML, By Acting on the Oxphos and Wnt Endpoints of Syk and p62SQSTM1 Pathways Prohibits Protective Autophagy; While Downregulation of NRF2, NQO1, Jun, and b-Catenin Bypasses Interfering RAS or WT1 Co-Mutations

Academic Article

Published In

  • Blood  Journal
  • Keywords

  • Genetics, Pediatric, Rare Diseases, Cancer, 2.1 Biological and endogenous factors, Cancer
  • Digital Object Identifier (doi)

    Pubmed Id

  • 3144064
  • Author List

  • Rangaraju S; Marino S; Roodman GD; Cripe LD; Ramdas B; Palam LR; Sargent KJ; Sayar H; Konig H; Kapur R
  • Start Page

  • 5051
  • End Page

  • 5051
  • Volume

  • 134
  • Issue

  • Supplement_1