Apathy is Associated with Critical Psychological Determinants of Medication Adherence in HIV Disease

Academic Article


  • Apathy is common in HIV, separable from depression, and has been associated with non-adherence to antiretroviral therapy (ART). We examined the associations between apathy and critical psychological determinants of ART adherence, as per the information-motivation-behavioral model, in 85 persons living with HIV. Apathy was measured using a composite of the apathy subscale of the Frontal Systems Behavioral Scale and the vigor-activation scale of the Profile of Mood States. Independent of major depressive disorder, apathy was related at small-to-medium effect sizes with motivation to adhere and self-efficacy for health-related┬ádecision-making and medication management, but not with HIV knowledge or medication management skills. These findings suggest that apathy plays a unique role in several critical health adherence determinants and support the importance of assessment and management of apathy to maximize health outcomes among individuals with HIV disease.
  • Digital Object Identifier (doi)

    Author List

  • Babicz MA; Woods SP; Fazeli P; Morgan EE
  • Start Page

  • 301
  • End Page

  • 312
  • Volume

  • 28
  • Issue

  • 2