Future treatments for hyperoxaluria

Academic Article

Abstract

  • Purpose of reviewThe review of potential therapies in the treatment of hyperoxaluria is timely, given the current excitement with clinical trials and the mounting evidence of the importance of oxalate in both kidney stone and chronic kidney disease.Recent findingsGiven the significant contribution of both endogenous and dietary oxalate to urinary oxalate excretions, it is not surprising therapeutic targets are being studied in both pathways. This article covers the existing data on endogenous and dietary oxalate and the current targets in these pathways.SummaryIn the near future, there will likely be therapies targeting both endogenous and dietary oxalate, especially in subsets of kidney stone formers.
  • Published In

    Digital Object Identifier (doi)

    Author List

  • Burns Z; Knight J; Fargue S; Holmes R; Assimos D; Wood K
  • Start Page

  • 171
  • End Page

  • 176
  • Volume

  • 30
  • Issue

  • 2