Long-term seizure freedom following intracranial sEEG monitoring: Therapeutic benefit of a diagnostic technique

Academic Article


  • Patients with treatment-resistant epilepsy often require surgery. It is very rare that patients with TRE can have sustained seizure freedom spontaneously, without undergoing further resection or neuro-modulation after invasive monitoring with sEEG. Of the 78 TRE cases monitored over last 5 years, we identified three patients who became seizure-free following sEEG monitoring without undergoing further resection or neuro-modulation. Seizure-freedom after sEEG is possible even without further intervention. In cases where seizures after the completion of the invasive monitoring are not observed, a longer observation period following electrode explantation prior to planned neuro-modulation or resection is warranted. This could be due to the disruption of the cortical–subcortical epileptogenic network due to focal area of tissue damage along and around the electrode tract.
  • Digital Object Identifier (doi)

    Author List

  • Kaur M; Szaflarski JP; Ver Hoef L; Pati S; Riley KO; Jaisani Z
  • Volume

  • 12