Glucagon regulation of energy expenditure

Academic Article

Abstract

  • © 2019 by the authors. Licensee MDPI, Basel, Switzerland. Glucagon’s ability to increase energy expenditure has been known for more than 60 years, yet the mechanisms underlining glucagon’s thermogenic effect still remain largely elusive. Over the last years, significant efforts were directed to unravel the physiological and cellular underpinnings of how glucagon regulates energy expenditure. In this review, we summarize the current knowledge on how glucagon regulates systems metabolism with a special emphasis on its acute and chronic thermogenic effects.
  • Authors

    Digital Object Identifier (doi)

    Pubmed Id

  • 26636907
  • Author List

  • Kleinert M; Sachs S; Habegger KM; Hofmann SM; Müller TD
  • Volume

  • 20
  • Issue

  • 21