Ketosis Ameliorates Renal Cyst Growth in Polycystic Kidney Disease

Academic Article


  • © 2019 Elsevier Inc. Dietary interventions that induce a state of ketosis were found to inhibit disease progression in animal models of polycystic kidney disease (PKD), a commonly inherited disease that leads to kidney failure. The beneficial effects of a ketogenic diet on PKD could be replicated in pre-clinical models by oral treatment with the natural ketone β-hydroxybutyrate.
  • Authors

    Digital Object Identifier (doi)

    Author List

  • Torres JA; Kruger SL; Broderick C; Amarlkhagva T; Agrawal S; Dodam JR; Mrug M; Lyons LA; Weimbs T
  • Start Page

  • 1007
  • End Page

  • 1023.e5
  • Volume

  • 30
  • Issue

  • 6