A meta-analytic review of 16 studies of the Youth Fit For Life obesity prevention intervention found an overall significant body mass index (BMI) reduction effect (r=.07) in the intended 5- to 12-year-old age range. Possible moderation of effects on BMI by participants' age, ethnicity, gender, intervention administration format, and publication status was tested. Only ethnicity was found to be a significant moderator, with minority participants having significantly larger effects than White participants. The overall effect size was larger than overall effects on BMI in a recent comprehensive meta-analysis of 64 child and adolescent obesity prevention intervention studies (r=.04) (Stice, Shaw, & Marti, 2006), and overall effects in a subset of 45 of those studies with ages consistent with the Youth Fit For Life studies. In that case, the effect size (r=.01) was not significantly different from zero. When moderators were contrasted between meta-analyses, Youth Fit For Life studies had larger effects for participants who were ages 8 through 12 years, and when physical activity participation was mandated. Implications for child obesity prevention research and interventions were discussed. © 2010 Taylor & Francis.