PURPOSE: The aim of this study was to establish a new method of facial soft tissue analysis based on 3dMDface system and to find the different esthetic preferences of Chinese beauties from the Chinese and Indian evaluators perspective. METHODS: Three-dimensional facial images of 242 females and 168 males were evaluated and ranked by 8 Chinese and nine Indians using a 10-point visual analog scale (VAS). Total 120 subjects in 2 panels (from Chinese perspective and Indian perspective) including 30 male and 30 female faces with top 30 scores were analyzed with the "average face" method respectively. Then 17 linear measurements, 13 curve measurements and 14 ratios of 4 average faces were calculated and compared with the divine proportion. RESULTS: Distinct differences were founded based on the average face analysis. Similar total facial types were preferred by both Chinese and Indian evaluators, while Indian evaluators preferred a wider male face with a protrusive lower lip. Delicate noses with lower nose ridge but protrusive lower lips in females were more acceptable by Indian evaluators. The differences of linear measurements were limited in 2.0 mm except the facial width, lower facial width, upper facial height and forehead height while curve measurements differ distinctly as the table shows. No ratios equal to the divine proportion were founded. CONCLUSION: The 3D Average face based on stereophotogrammetry is a feasible method to analyze the facial characters and discrepancy of esthetic preferences. Chinese and Indian evaluators have some certain differences when judging beauties. Attractive faces have some certain ratios but not the divine proportion.This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0.