Fatal haemorrhage following liver biopsy in patients with HIV infection

Academic Article


  • A retrospective review of all 248 liver biopsies performed in patients with HIV infection at two referral centres in London over a 12 year period revealed five cases of major bleeding following biopsy, with four deaths. The risk of major bleeding was 2.0%, and mortality was 1.6% following liver biopsy. The risk of bleeding was much higher than in published series of biopsies done in patients without HIV infection, owing in part to the high prevalence of thrombocytopaenia and clotting abnormalities in patients with HIV infection. HIV infection per se may also increase the risk of bleeding following liver biopsy.
  • Published In

    Digital Object Identifier (doi)

    Pubmed Id

  • 21672160
  • Author List

  • Churchill DR; Mann D; Coker RJ; Miller RF; Glazer G; Goldin RD; Lucas SB; Weber JN; De Cock KM
  • Start Page

  • 62
  • End Page

  • 64
  • Volume

  • 72
  • Issue

  • 1