Efficacy of boosted protease inhibitor monotherapy in patients with complex medical problems

Academic Article

Abstract

  • The efficacy of boosted protease inhibitor monotherapy (BPIm) in HIV-positive patients with complex medical problems was assessed in ten patients. With BPIm, median (range) HIV viral load reduction was log10 2.15 (1.62-3.1) by 4-8 weeks; in four patients, viral load was < 400 copies/ml. During follow-up, at median (range) = 50 (8-156) weeks, no patient had an opportunistic illness; one patient developed new PI mutations after 48 weeks. These very preliminary data need further confirmation on a larger scale. © 2007 Lippincott Williams & Wilkins, Inc.
  • Authors

    Published In

  • AIDS  Journal
  • Digital Object Identifier (doi)

    Author List

  • Garrett NJ; Matin N; Edwards SG; Miller RF
  • Start Page

  • 1821
  • End Page

  • 1823
  • Volume

  • 21
  • Issue

  • 13