Chronic myelomonocytic leukemia associated with myeloid sarcomas and NPM1 mutation: a case report and literature review

Academic Article


  • We present a case of chronic myelomonocytic leukemia (CMML) associated with myeloid sarcomas. The CMML also harbored a NPM1 mutation, which is uncommonly described outside the context of acute myeloid leukemia (AML). We describe our treatment strategy, which involved remission-induction chemotherapy that led to rapid resolution of myeloid sarcomas, and we present a literature review highlighting the treatment challenges that similar cases pose.
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    Digital Object Identifier (doi)

    Author List

  • Matanes F; Abdelazeem BMA; Shah G; Reddy V; Saad A; Papadantonakis N
  • Start Page

  • 1
  • End Page

  • 9
  • Volume

  • 10