Gene therapy for ocular neovascularization: A cure in sight

Academic Article


  • Recent advances in the field of ocular gene transfer have led researchers pursuing treatment for age-related macular degeneration and diabetic retinopathy to turn to gene therapy for the answer. Viral vector-mediated delivery of both anti-angiogenic proteins and molecules that inhibit the eye's endogenous pro-angiogenic factors has successfully diminished the pathology of ocular diseases in rodent models. A gene-therapy solution to the debilitating blindness caused by ocular neovascularization may be on the horizon.
  • Authors

    Digital Object Identifier (doi)

    Author List

  • Reich SJ; Bennett J
  • Start Page

  • 317
  • End Page

  • 322
  • Volume

  • 13
  • Issue

  • 3