Retinas in a Dish Peek into Inherited Retinal Degeneration

Academic Article

Abstract

  • © 2016 Elsevier Inc. Human retinal degeneration can cause blindness, and the lack of relevant model systems has made identifying underlying mechanisms challenging. Parfitt et al. (2016) generate three-dimensional retinal tissue from patient-derived induced pluripotent stem cells to identify how CEP290 mutations cause retinal degeneration, and show an antisense approach can correct disease-associated phenotypes.
  • Authors

    Digital Object Identifier (doi)

    Pubmed Id

  • 8743469
  • Author List

  • Duong TT; Vasireddy V; Mills JA; Bennett J
  • Start Page

  • 688
  • End Page

  • 689
  • Volume

  • 18
  • Issue

  • 6