Defining Barriers that Impede Choices

Academic Article


  • Committing to a differentiation pathway means leaving alternative pathways behind. Adoue et al. (2019) report that the H3K9-methyltrasferase Setdb1 plays a role in inhibiting the Th1 program in committed Th2 cells, and mechanistically, its role might relate to the selective targeting of endogenous retroviruses adjacent to Th1 enhancers.
  • Published In

  • Immunity  Journal
  • Digital Object Identifier (doi)

    Author List

  • Webb TJ; Weinmann AS
  • Start Page

  • 542
  • End Page

  • 544
  • Volume

  • 50
  • Issue

  • 3