Development and validation of the lupus impact tracker: A patient-completed tool for clinical practice to assess and monitor the impact of systemic lupus erythematosus

Academic Article


  • Methods. Items for the LIT were selected from the LupusPRO, a validated patient-reported outcomes measure, using 3 approaches: confirmatory factor analysis (CFA), stepwise regression, and patient focus groups. CFA was conducted to find items from the LupusPRO that fit a unidimensional structure to allow scoring as a single index. Stepwise regression methods identified items with the strongest relationship (convergent validity) with disease activity measures and patient health rating. Focus groups (n = 26 patients) identified the most important items describing SLE impact. Selected items were evaluated for reliability and validity.
  • Published In

    Digital Object Identifier (doi)

    Pubmed Id

  • 22172591
  • Author List

  • Jolly M; Garris CP; Mikolaitis RA; Jhingran PM; Dennis G; Wallace DJ; Clarke A; Dooley MA; Parke A; Strand V
  • Start Page

  • 1542
  • End Page

  • 1550
  • Volume

  • 66
  • Issue

  • 10