© 2018 Elsevier Inc. All rights reserved. Although conservative breast surgery is favored for the treatment of early stage breast cancer, mastectomy still has a place in the armamentarium of the surgeon. In the case of T3, multicentric, and inflammatory breast cancer, it is the treatment of choice. From the patient's point of view, it is a good choice if they don't want to or cannot have radiation therapy. It can be accompanied by skin sparing and nipple skin sparing techniques and reconstruction to improve the aesthetic outcome.