Diabetes: hydrogen-bonded multilayers of tannic Acid as mediators of T-cell immunity (adv. Healthcare mater. 5/2015).

Academic Article


  • Nanothin hydrogen-bonded multilayers of natural polyphenol, tannic acid, presented by H. M. Tse, E. Kharlampieva, and colleagues on page 686 possess dual antioxidant and immunosuppressive properties. In particular, the coating efficiently dissipates pro-inflammatory reactive oxygen and nitrogen species and attenuates the production of pro-inflammatory cytokines, which may provide physical transplant protection and prevent diabetogenic autoreactive T-cell responses in Type 1 diabetes patients.
  • Published In


  • antioxidants, hydrogen-bonded multilayers, immunomodulatory, poly(N-vinylpyrrolidone), tannic acid, type-1 diabetes
  • Digital Object Identifier (doi)

    Author List

  • Kozlovskaya V; Xue B; Lei W; Padgett LE; Tse HM; Kharlampieva E
  • Start Page

  • 685
  • Volume

  • 4
  • Issue

  • 5