Protective effects of calcium channel blockers in cardiac surgery

Academic Article

Abstract

  • Calcium plays an essential role in ischemic events observed during cardiac surgery. Many experiments have studied the effects of calcium channel blockers on intracellular calcium overload during the periods of cardiac ischemia and reperfusion. Calcium channel blockers are no longer used before and during cardiac surgery because hypothermia inhibits their pharmacological action. However, during the post-operative period, calcium channel blockers are the drugs of choice to control coronary spasm, and arterial hypertension which is secondary to peripheral vasoconstriction.
  • Published In

  • Therapies  Journal
  • Pubmed Id

  • 23856274
  • Author List

  • Piwnica A; Menasche P
  • Start Page

  • 171
  • End Page

  • 174
  • Volume

  • 44
  • Issue

  • 3