The in vitro uptake of lysine and alanine by human jejunal mucosa in nutritional rickets

Academic Article


  • In some congenital and acquired conditions, aminoaciduria is associated with defective absorption by the mucosa of the small intestine. There is generalised aminoaciduria in nutritional rickets; thus, jejunal function was investigated. Epithelium from six patients was incubated with a dilute solution of radioactively labelled lysine and alanine. The concentration in the tissue, compared with that in the medium, was a measure of the uptake which, in turn, was thought to parallel the absorptive capacity of the gut. In the conditions of these observations, no impairment of uptake was demonstrated. © 1973 by S. Karger AG, Basel.
  • Authors

    Digital Object Identifier (doi)

    Pubmed Id

  • 15336569
  • Author List

  • Woodd-Walker RB; Hansen JDL; Saunders SJ
  • Start Page

  • 155
  • End Page

  • 162
  • Volume

  • 15
  • Issue

  • 3