The MMPI profiles of 123 male and 221 female patients with multiple pain complaints referred for psychological evaluation over a three-year period were examined using a multivariate clustering technique. Replicable subgroups were found in the patient cohorts in both the male and female samples. Multiple discriminant analysis and analysis of variance showed that the subgroups differed significantly from one another and within subgroup variation was small relative to between subgroup variation. It is suggested that pain patients are characterized by a variety of personality styles; subgroup membership may be an indication of behavior and personality dynamics which may have implications for treatment selection. Inferences as to possible treatment responses based on subgroup membership are made. © 1980, Taylor & Francis Group, LLC. All rights reserved.