Melanotic schwannoma of bone. Clinicopathologic, immunohistochemical, and ultrastructural features of a rare primary bone tumor

Academic Article


  • The authors report a 35-year-old woman who presented with a lytic and blastic tumor of the ilium with soft tissue extension. The resected tumor showed light microscopic and ultrastructural features characteristic of a melanotic schwannoma. An unusual histologic finding was the presence of laminated concretions resembling psammoma bodies. Immunohistochemical stains for S-100, HMB-45, and vimentin were strongly positive. The patient is free of disease 18 months after complete surgical excision.
  • Digital Object Identifier (doi)

    Author List

  • Myers JL; Bernreuter W; Dunham W
  • Start Page

  • 424
  • End Page

  • 429
  • Volume

  • 93
  • Issue

  • 3