© 2018 Elsevier Inc. Many of the enhanced recovery after surgery principles initially developed for colorectal surgery can be successfully applied to gynecologic oncology and lead to significant improvements in perioperative care. Enhanced recovery after surgery guidelines specific to gynecologic oncology were published in 2016 and provide a framework for the development and implementation of institutional protocols. Identification of key stakeholders and a multidisciplinary approach are critical to identifying which principles are best suited for implementation at a particular institution and for ensuring success of the protocol. Herein, we review our experience with protocol development and implementation on a gynecologic oncology service.