Patent foramen ovale closure for cryptogenic stroke: Effective, but only in select patients

Academic Article


  • PFO closure reduces risk of recurrent stroke in some patients with cryptogenic stroke, particularly younger patients <45 years with moderate or greater right to left shunting Number needed to treat (NNT) to prevent one stroke at 5 years are 28 to 69 (95% confidence limits of 21 to 351) suggesting need for individualized risk stratification models PFO closure may increase short- and possibly long-term risk of atrial flutter/fibrillation.
  • Digital Object Identifier (doi)

    Author List

  • Chatterjee A; Hillegass WB
  • Start Page

  • 174
  • End Page

  • 175
  • Volume

  • 92
  • Issue

  • 1