Developing photolabile protecting groups based on the excited state meta effect

Academic Article


  • We have recently developed a number of photolabile protecting groups (PPGs) for efficient release of carbonyl, hydroxyl, diol, carboxyl, and amino functionalities. These new PPGs are designed on the basis of the excited state meta effect. They share common features including structural simplicity, easy preparation, flexible structural modification, diverse protection methods, high protection and deprotection efficiency, tolerance of ambient conditions during irradiation, and remarkable stability toward chemical treatments. They can be potentially useful in a wide range of applications including organic synthesis, caging, and materials science.
  • Digital Object Identifier (doi)

    Author List

  • Wang P
  • Start Page

  • 300
  • End Page

  • 310
  • Volume

  • 335