The role of cytokines and pathogen recognition molecules in fungal keratitis - Insights from human disease and animal models.

Academic Article

Abstract

  • Fungal infections of the cornea are an important cause of blindness and visual impairment worldwide, with contact lens wear being the main risk factor in the USA and other industrialized countries, and traumatic injury being the main risk factor in developing countries. In this review, we highlight recent advances in the understanding of the host response to Aspergillus and Fusarium species in infected human corneal tissue and in mouse models of fungal keratitis.
  • Authors

    Keywords

  • Animals, Contact Lenses, Cornea, Cytokines, Disease Models, Animal, Eye Infections, Fungal, Fusarium, Humans, Keratitis, Lectins, C-Type, Mice, Mycoses, Toll-Like Receptor 4
  • Digital Object Identifier (doi)

    Author List

  • Leal SM; Pearlman E
  • Start Page

  • 107
  • End Page

  • 111
  • Volume

  • 58
  • Issue

  • 1